Asthma rESEARCH

The BREATHE Center was originally established as the Center for Childhood Asthma in the Urban Environment in 1998. This Center is one of the original NIEHS and EPA funded Children’s Centers and has focused on childhood asthma and respiratory disease for over twenty years. The Center has have made significant contributions to defining environmental risk factors and developing interventions to reduce risk. Studies have demonstrated that indoor air pollution is a driver of childhood asthma in Baltimore City and identified strategies to reduce air pollution exposures for the sake of improving health. Our work has also demonstrated that mouse allergen exposure is linked to increased asthma emergency visits and hospitalizations among those who are sensitized. We have identified overweight and obesity as susceptibility factors for the adverse effects of air pollution. Center studies have also demonstrated that dietary intake of fatty acid likely modifies pollution susceptibility- omega 6 intake with a potentially harmful and omega 3 intake with a protective effect. We have extended our work to focus on children and adults, to include home and school environments, and to define practical interventions to address environmental health disparities. We continue to work to reduce the burden in asthma in our community and similar communities across the country.

Interested in Participating in Asthma Research Studies?

Call 410-955-1530

Actively Enrolling Participants

D.R.E.A.M. Determining the Relationship between Environment, sleep, and AsthMa - Pediatric Research

D.R.E.A.M. is seeking children between the ages of 8-17 years old with a diagnosis of asthma to participate in a pediatric asthma research study. This research is being done to examine the link between environmental exposures and sleep patterns in children with asthma.

Participants will be asked to complete 3 in-person clinic visits at Johns Hopkins Asthma & Allergy Center. As well as 3 one-week home air monitoring periods each including a one-night in-home sleep study.

Transportation to and from clinic visits will be provided. Participants will receive up to $475.00 in monetary payments and gift cards.

Principal Investigator: Meredith McCormack, MD MHS

IRB00290724

If you are interested in learning more about the study, please contact D.R.E.A.M. staff via email or phone.

Email Research Staff

Call D.R.E.A.M. Staff at 410-955-1530

MINA: Metformin in Asthma Research Study

This is a randomized clinical trial of metformin consisting of four in-person, four telephone, and four video visits over 7 months. Adults who are overweight or obese and have asthma that is not well-controlled may be eligible to participate.

Participants will be asked to answer questionnaires related to their health and asthma control, submit blood and urine samples, and complete lung function tests. Participants will receive up to $535.00 in monetary payments.

Principal Investigator: Meredith McCormack, MD MHS

IRB Approval: IRB00409080

If you are interested in learning more about the study, please contact MINA Research staff via email or phone.

Email MINA Research Staff

Call MINA Research Staff at 410-955-1530

The Johns Hopkins Asthma Center Registry Research Study

The Asthma Center Registry Research Study is seeking adults over 18 years old with asthma or suspected asthma to participate in an asthma research registry.

The overall goal of the Johns Hopkins Asthma Center is to improve the health and quality of life of patients living with asthma. The Johns Hopkins Asthma Center Registry provides the ability to learn from patients and align clinical care and research to increase our understanding of asthma and to identify new treatments and approaches to care for asthma. The purpose of this study is to develop a registry of biological samples and health information from patients with asthma and pulmonary disorders. Individuals without an asthma diagnosis will also be included to serve as a comparison group.

Principal Investigator: Meredith McCormack, MD MHS

IRB00283885

If you are interested in learning more about the study, please contact Registry staff via email or phone.

Email Registry Staff

Call Registry Staff at 410-955-1530

Asthma rESEARCH

Actively Enrolling Participants

D.R.E.A.M. Determining the Relationship between Environment, sleep, and AsthMa - Pediatric Research

MINA: Metformin in Asthma Research Study

The Johns Hopkins Asthma Center Registry Research Study

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